Structural characterization of the O-antigenic polysaccharide from the lipopolysaccharide of Vibrio cholerae O37
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چکیده
The chemical structure of the O-antigenic polysaccharide isolated from the lipopolysaccharide of Vibrio cholerae O37 by mild acid hydrolysis was elucidated. The O-antigenic polysaccharide is found to consist of D-glucose, N-acetyl-D-Quinovosamine and small amount of 4-O-methyl-N-acetyl-D-quinovasamine. The structure of the O-antigen is established by using sugar and methylation analyses, Smith degradation studies and by using GLC, GC-MS, FAB-MS, one dimensional H and C NMR spectroscopy and two dimensional NMR spectroscopy including COSY, TOCSY, HSQC, experiments.
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تاریخ انتشار 2009